CAS No.: | 83915-83-7 |
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Fórmula: | c21h31n3o5 |
EINECS: | 627-033-9 |
Tipo: | Intermediários Farmacêuticos |
Aparência: | Pó |
Qualidade: | Refinado |
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High Quality Lisinopril Dihydrate CAS 83915-83-7
Product Name: Lisinopril Dihydrate
Synonyms: Lisinopril Related Compound A (15 mg) ((S)-2-{(3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl}-4-phenylbutanoic acid);(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate;LIQUID PRED (predniso ne),Lisinopril;Lisinopril API;Lisinopril (Zestril);Lisinopril for system suitability A;Lisinopril for peak identification;N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline,hydrate (1:2)
CAS: 83915-83-7
MF: C21H31N3O5
MW: 405.49
EINECS: 627-033-9
Product Categories: Active Pharmaceutical Ingredients;Drug bulk;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Angiotensin;ZESTRIL;Cardiovascular APIs
Mol File: 83915-83-7.mol
Lenopril is a third generation angiotensin-converting enzyme inhibitor, a lysine derivative of Enalapril, which was marketed in the United States in 1987 for the treatment of hypertension and is the first-line treatment for anti-hypertensive disease. It is similar to Enalapril in terms of pharmacological action and has a strong angiotensin-converting enzyme inhibitory effect, with rapid onset and long duration of action. The inhibitory effect on ACE is 6-8 times that of captopril and 1-3 times that of benazepril. It can cause a significant decrease in total peripheral resistance and blood pressure, but is not accompanied by reflex tachycardia. Lenopril can lower pulmonary wedge pressure, increase cardiac beat volume, increase left ventricular ejection fraction and improve cardiac function in patients with heart failure. It can increase renal blood flow, reduce renal vascular resistance, and increase glomerular filtration rate.
Lisinopril Dihydrate CAS 83915-83-7 of Chemical Properties
Melting point 148 °C
alpha 25405 -120° (c = 1 in 0.25M pH 6.4 zinc acetate); 25436 -96° (c = 1 in 0.25M pH 6.4 zinc acetate)
refractive index -45 ° (C=1, 0.25mol/L Zinc Acetate Buffer)
storage temp. 2-8°C
solubility H2O: ≥10 mg/mL
form solid
pka 2.5, 4.0, 6.7, 10.1(at 25ºC)
color white
Merck 14,5516
Stability: Hygroscopic
CAS DataBase Reference 83915-83-7(CAS DataBase Reference)
EPA Substance Registry System L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, hydrate (1:2) (83915-83-7)
Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
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